Neuroleptic drugs also known as antipsychotics are a a group of drugs used to treat psychosis which is typified by schizophreniaover time a wide range of antipsychotics have been developed a first generation of antipsychotics known as typical antipsychotics was discovered in the 1950smost of the drugs in the second generation known as atypical antipsychotics recently have been developed. Antipsychotics are drugs that are used to treat symptoms of psychosis such as delusions for example hearing voices hallucinations paranoia or confused thoughts they are used in the treatment of schizophrenia severe depression and severe anxiety antipsychotics are also useful at stabilizing episodes of mania in people with bipolar disorder. The reverse holds true for the xr version as the peak effect is delayed and thus the patient can experience residual sedation during the day the antipsychotic action is of longer duration more extended d2 receptor occupancy and hence can be used as an antipsychotic. It is proposed that this is the site at which classical neuroleptic drugs exert their indirect action leading to their therapeutic benefits it is well established that many patients with psychotic illnesses fail to benefit from classical neuroleptic drugs sometimes this feature is present right at the start of the illness while in other
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